RING2 Rabbit Polyclonal Antibody

• Background:

  E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals.

• Product Name Alternative:

  BAP1; DING; BAP-1; HIPI3; RING2; RING1B

• Gene Name:

  RNF2

• Gene ID:

  6045

• Swiss Prot:

  Q99496

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, ICC/IF, FC

• Field of Research:

  Epigenetics and Nuclear Signaling

• Purification:

  Affinity Chromatography

• Dilution:

  WB 1:500-1:1000, IHC 1:50-1:100, ICC/IF 1:50-1:200, FC 1:50-1:100

• Form:

  Liquid

• Buffer:

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 38 kDa; Observed MW: 38 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype:

  IgG