Mre11 Rabbit Polyclonal Antibody

• Background:

  DNA double-strand breaks are generated by ionizing radiation and endogenously produced radicals, and they often are repaired through the RAD52 homologous recombination pathway. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity.

• Product Name Alternative:

  MRE11 homolog 1; Meiotic recombination 11 homolog A; MRE11 homolog A; MRE11A; HNGS1; MRE11

• Gene Name:

  MRE11

• Gene ID:

  4361

• Swiss Prot:

  P49959

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC

• Field of Research:

  Epigenetics and Nuclear Signaling

• Purification:

  Affinity Chromatography

• Dilution:

  WB 1:500-1:1000, IHC 1:50-1:100

• Form:

  Liquid

• Buffer:

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 81 kDa; Observed MW: 81 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype:

  IgG