Cyclin E2 Rabbit Polyclonal Antibody

• Background:

  The human Cyclin E2 gene encodes a 404 amino acid protein that is most closely related to Cyclin E. Cyclin E2 mRNA levels peaks at the G1 / S transition. Cyclin E2 associates with Cdk2 in a functional kinase complex that is inhibited by both p27 (Kip1) and p21 (Cip1) . Cyclin E2 / Cdk2 phosphorylates histone H1 in vitro. G1 cyclin E controls the initiation of DNA synthesis by activating CDK2. Abnormally high levels of cyclin E expression have frequently been observed in human cancers.

• Product Name Alternative:

  CCNE2; G1/S-specific cyclin-E2

• Gene Name:

  CCNE2

• Gene ID:

  9134

• Swiss Prot:

  O96020

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, ICC/IF, FC

• Field of Research:

  Cell Biology

• Purification:

  Affinity Chromatography

• Dilution:

  WB 1:500-1:1000, IHC 1:50-1:100, ICC/IF 1:50-1:200, FC 1:50-1:100

• Form:

  Liquid

• Buffer:

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 47 kDa; Observed MW: 47 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype:

  IgG