CDT2 Rabbit Polyclonal Antibody

• Background:

  Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX (DTL) complex, also named CRL4 (CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1 and CDKN1A/p21 (CIP1) .

• Product Name Alternative:

  CDW1; DCAF2; Dtl; L2DTL; RAMP

• Gene Name:

  DTL

• Gene ID:

  51514

• Swiss Prot:

  Q9NZJ0

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, ICC/IF, FC

• Field of Research:

  Cell Biology

• Purification:

  Affinity Chromatography

• Dilution:

  WB 1:500-1:1000, IHC 1:50-1:100, ICC/IF 1:50-1:200, FC 1:50-1:100

• Form:

  Liquid

• Buffer:

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 79 kDa; Observed MW: 91 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype:

  IgG