Z280B Rabbit Polyclonal Antibody

• Background:

  The protein encoded by this gene is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, but only one of them is protein-coding. [provided by RefSeq, Jan 2015], function:May function as a transcription factor., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 4 C2H2-type zinc fingers.

• Gene Name:

  ZNF280B SUHW2 ZNF279 ZNF632

• Gene ID:

  140883

• Swiss Prot:

  Q86YH2

• Host:

  Rabbit

• Reactivity:

  Human, Rat, Mouse

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB, ELISA

• Purification:

  Affinity purification

• Dilution:

  WB 1:500-1:2000, ELISA 1:5000-1:20000

• Form:

  Liquid

• Buffer:

  Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

• Modification:

  Unmodified

• Molecular Weight:

  59kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype:

  IgG