CTAG2 Rabbit Polyclonal Antibody

• Background :

  This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID:10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013], domain:A transmembrane domain is present in isoform LAGE-1A., similarity:Belongs to the CTAG family., tissue specificity:Testis and very low level in placenta and in some uterus samples. Observed in 25-50% of tumor samples of melanomas, non-small-cell lung carcinomas, bladder, prostate and head and neck cancers.

• Gene Name :

  CTAG2 ESO2 LAGE1

• Gene ID :

  30848

• Swiss Prot :

  O75638

• Host :

  Rabbit

• Reactivity :

  Human, Rat, Mouse

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB, ELISA

• Purification :

  Affinity purification

• Dilution :

  WB 1:500-1:2000, ELISA 1:5000-1:20000

• Form :

  Liquid

• Buffer :

  Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

• Modification :

  Unmodified

• Molecular Weight :

  23kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype :

  IgG