NFE2 Rabbit Polyclonal Antibody

• Background:

  Function:Required for activity at the locus control region (LCR) upstream of the globin gene complexes. Requires p18 NF-E2 for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production: globin synthesis, heme synthesis, and the procurement of iron., similarity:Belongs to the bZIP family., similarity:Belongs to the bZIP family. CNC subfamily., similarity:Contains 1 bZIP domain., subunit:Interacts with MLL2; leading to activate transcription of the beta-globin locus (By similarity) . Heterodimer of p45 NF-E2 and p18 NF-E2. Forms high affinity heterodimer with MAFG; the interaction promotes erythropoiesis., tissue specificity:Expressed in hematopoietic cells and also in colon and testis., function:Required for activity at the locus control region (LCR) upstream of the globin gene complexes. Requires p18 NF-E2 for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production: globin synthesis, heme synthesis, and the procurement of iron., similarity:Belongs to the bZIP family., similarity:Belongs to the bZIP family. CNC subfamily., similarity:Contains 1 bZIP domain., subunit:Interacts with MLL2; leading to activate transcription of the beta-globin locus (By similarity) . Heterodimer of p45 NF-E2 and p18 NF-E2. Forms high affinity heterodimer with MAFG; the interaction promotes erythropoiesis., tissue specificity:Expressed in hematopoietic cells and also in colon and testis.

• Gene Name:

  NFE2

• Gene ID:

  4778

• Swiss Prot:

  Q16621

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB, ELISA

• Purification:

  Affinity purification

• Dilution:

  WB 1:500-1:2000, ELISA 1:5000-1:20000

• Form:

  Liquid

• Buffer:

  Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

• Modification:

  Unmodified

• Molecular Weight:

  41kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype:

  IgG