NFE2 Rabbit Polyclonal Antibody

CAT: 1444-APRab14646-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:1444-APRab14646-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Required for activity at the locus control region (LCR) upstream of the globin gene complexes. Requires p18 NF-E2 for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production: globin synthesis, heme synthesis, and the procurement of iron., similarity:Belongs to the bZIP family., similarity:Belongs to the bZIP family. CNC subfamily., similarity:Contains 1 bZIP domain., subunit:Interacts with MLL2; leading to activate transcription of the beta-globin locus (By similarity) . Heterodimer of p45 NF-E2 and p18 NF-E2. Forms high affinity heterodimer with MAFG; the interaction promotes erythropoiesis., tissue specificity:Expressed in hematopoietic cells and also in colon and testis., function:Required for activity at the locus control region (LCR) upstream of the globin gene complexes. Requires p18 NF-E2 for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production: globin synthesis, heme synthesis, and the procurement of iron., similarity:Belongs to the bZIP family., similarity:Belongs to the bZIP family. CNC subfamily., similarity:Contains 1 bZIP domain., subunit:Interacts with MLL2; leading to activate transcription of the beta-globin locus (By similarity) . Heterodimer of p45 NF-E2 and p18 NF-E2. Forms high affinity heterodimer with MAFG; the interaction promotes erythropoiesis., tissue specificity:Expressed in hematopoietic cells and also in colon and testis.
Gene Name
NFE2
Gene ID
4778
Swiss Prot
Q16621
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
41kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG

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