Tip5 Rabbit Polyclonal Antibody

• Background :

  Function:May play a role in transcriptional regulation interacting with ISWI. May serve a specific role in maintaining or altering the chromatin structure of the rDNA locus., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., sequence caution:Contaminating sequence. Potential poly-A sequence., similarity:Belongs to the WAL family., similarity:Contains 1 bromo domain., similarity:Contains 1 DDT domain., similarity:Contains 1 MBD (methyl-CpG-binding) domain., similarity:Contains 1 PHD-type zinc finger., similarity:Contains 4 A.T hook DNA-binding domains., subcellular location:Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus., subunit:Together with SMARCA5, it forms a complex termed NoRC (nucleolar remodeling complex) ., tissue specificity:Expressed at moderate levels in most tissues analyzed, including heart, brain, placenta, lung, skeletal muscle, kidney and pancreas., function:May play a role in transcriptional regulation interacting with ISWI. May serve a specific role in maintaining or altering the chromatin structure of the rDNA locus., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., sequence caution:Contaminating sequence. Potential poly-A sequence., similarity:Belongs to the WAL family., similarity:Contains 1 bromo domain., similarity:Contains 1 DDT domain., similarity:Contains 1 MBD (methyl-CpG-binding) domain., similarity:Contains 1 PHD-type zinc finger., similarity:Contains 4 A.T hook DNA-binding domains., subcellular location:Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus., subunit:Together with SMARCA5, it forms a complex termed NoRC (nucleolar remodeling complex) ., tissue specificity:Expressed at moderate levels in most tissues analyzed, including heart, brain, placenta, lung, skeletal muscle, kidney and pancreas.

• Product Name Alternative :

  BAZ2A; KIAA0314; TIP5; Bromodomain adjacent to zinc finger domain protein 2A; Transcription termination factor I-interacting protein 5; TTF-I-interacting protein 5; Tip5; hWALp3

• Gene Name :

  BAZ2A

• Gene ID :

  605682

• Swiss Prot :

  Q9UIF9

• Host :

  Rabbit

• Reactivity :

  Human, Rat, Mouse

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB, IHC

• Purification :

  Affinity purification

• Dilution :

  WB 1:500-1:2000, IHC 1:50-1:300

• Form :

  Liquid

• Buffer :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

• Modification :

  Unmodified

• Molecular Weight :

  210kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype :

  IgG