BAGE5 Rabbit Polyclonal Antibody

• Background :

  The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], function:Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2., similarity:Contains 4 BAG domains., subunit:Binds to the ATPase domain of HSP70/HSC chaperones. Binds PARK2.

• Product Name Alternative :

  BAG5; KIAA0873; BAG family molecular chaperone regulator 5; BAG-5; Bcl-2-associated athanogene 5

• Gene Name :

  BAG5

• Gene ID :

  9529

• Swiss Prot :

  Q9UL15

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB, ELISA

• Purification :

  Affinity purification

• Dilution :

  WB 1:500-1:2000, ELISA 1:5000-1:10000

• Form :

  Liquid

• Buffer :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

• Modification :

  Unmodified

• Molecular Weight :

  51kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype :

  IgG