ACO2 Rabbit Polyclonal Antibody

• Background:

  The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008], catalytic activity:Citrate = isocitrate., cofactor:Binds 1 4Fe-4S cluster per subunit. Binding of a 3Fe-4S cluster leads to an inactive enzyme., online information:Aconitase entry, pathway:Carbohydrate metabolism; tricarboxylic acid cycle., similarity:Belongs to the aconitase/IPM isomerase family., subunit:Monomer.

• Product Name Alternative:

  Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase)

• Gene Name:

  ACO2

• Gene ID:

  50

• Swiss Prot:

  Q99798

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Canine

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB, ELISA

• Field of Research:

  Citrate cycle (TCA cycle) ; Glyoxylate and dicarboxylate metabolism

• Purification:

  Affinity purification

• Dilution:

  WB 1:500-1:2000, ELISA 1:5000-1:10000

• Form:

  Liquid

• Buffer:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

• Modification:

  Unmodified

• Molecular Weight:

  90kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype:

  IgG