Eotaxin Rabbit Polyclonal Antibody

CAT: 1444-APRab10488-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:1444-APRab10488-01Size:20 µL
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Background
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014], function:In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3., induction:By TNF-alpha, interleukin-1 alpha and interferon gamma., online information:CCL11 entry, PTM:O-linked glycan consists of a Gal-GalNAc disaccharide which is mofified with up to 2 sialic acid residues., similarity:Belongs to the intercrine beta (chemokine CC) family.
Product Name Alternative
CCL11; SCYA11; Eotaxin; C-C motif chemokine 11; Eosinophil chemotactic protein; Small-inducible cytokine A11
Gene Name
CCL11
Gene ID
6356
Swiss Prot
P51671
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Field of Research
Cytokine-cytokine receptor interaction; Chemokine; NOD-like receptor; Asthma
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
11kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG

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