CyPB Rabbit Polyclonal Antibody

CAT: 1444-APRab09681-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:1444-APRab09681-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009], catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0) ., caution:It is uncertain whether Met-1 or Met-9 is the initiator., enzyme regulation:Cyclosporin A (CsA) inhibits CYPB., function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides., similarity:Belongs to the cyclophilin-type PPIase family. PPIase B subfamily., similarity:Contains 1 PPIase cyclophilin-type domain., subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Product Name Alternative
PPIB; CYPB; Peptidyl-prolyl cis-trans isomerase B; PPIase B; CYP-S1; Cyclophilin B; Rotamase B; S-cyclophilin; SCYLP
Gene Name
PPIB
Gene ID
5479
Swiss Prot
P23284
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
24kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG

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