CD80 Rabbit Polyclonal Antibody

• Background:

  The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011], function:Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor., similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain., similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain., subunit:Interacts with adenovirus subgroup B fiber proteins and acts as a receptor for these viruses., tissue specificity:Expressed on activated B-cells, macrophages and dendritic cells.

• Product Name Alternative:

  T-lymphocyte activation antigen CD80 (Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD antigen CD80)

• Gene Name:

  CD80 CD28LG CD28LG1 LAB7

• Gene ID:

  941

• Swiss Prot:

  P33681

• Host:

  Rabbit

• Reactivity:

  Human, Rat, Mouse

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC, ICC/IF, ELISA

• Field of Research:

  Cell adhesion molecules (CAMs) ; Toll_Like; Intestinal immune network for IgA production; Type I diabetes mellitus; Autoimmune thyroid disease; Systemic lupus erythematosus; Allograft rejection; Graft-versus-host disease; Viral myocarditis

• Purification:

  Affinity purification

• Dilution:

  IHC 1:50-1:200, ICC/IF 1:50-1:200, ELISA 1:10000-1:20000

• Form:

  Liquid

• Buffer:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

• Modification:

  Unmodified

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype:

  IgG