CdGAP Rabbit Polyclonal Antibody

CAT: 1444-APRab08537-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:1444-APRab08537-01Size:20 µL
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
This gene encodes a GTPase-activating protein (GAP) . A variety of cellular processes are regulated by Rho GTPases which cycle between an inactive form bound to GDP and an active form bound to GTP. This cycling between inactive and active forms is regulated by guanine nucleotide exchange factors and GAPs. The encoded protein is a GAP shown to regulate two GTPases involved in protein trafficking and cell growth. [provided by RefSeq, Jul 2008], developmental stage:Mainly expressed in fetal heart and muscle., function:Functions as a GTPase-activating protein (GAP) for RAC1 and CDC42. Required for cell spreading, polarized lamellipodia formation and cell migration., PTM:Phosphorylation on Thr-789 reduces GAP activity., similarity:Contains 1 Rho-GAP domain., subunit:Interacts with ITSN1, which inhibits GAP activity. Interacts with PARVA.
Product Name Alternative
ARHGAP31; CDGAP; KIAA1204; Rho GTPase-activating protein 31; Cdc42 GTPase-activating protein
Gene Name
ARHGAP31
Gene ID
57514
Swiss Prot
Q9ULL6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC, ICC/IF, ELISA
Purification
Affinity purification
Dilution
IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:5000-1:10000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG

Popular Products