EAT-2 Rabbit Polyclonal Antibody

• Background:

  By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]) .[supplied by OMIM, Mar 2008], function:Plays a role in controlling signal transduction through at least four receptors, CD84, CD150, CD229 and CD244, expressed on the surface of professional antigen-presenting cells., similarity:Contains 1 SH2 domain., subunit:Binds to the phosphorylated receptors CD84, CD150, CD229 and CD244. Does not bind to non-phosphorylated CD150.

• Product Name Alternative:

  SH2D1B; EAT2; SH2 domain-containing protein 1B; EWS/FLI1-activated transcript 2; EAT-2

• Gene Name:

  SH2D1B

• Gene ID:

  117157

• Swiss Prot:

  O14796

• Host:

  Rabbit

• Reactivity:

  Human, Rat, Mouse

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC, ICC/IF, ELISA

• Field of Research:

  Natural killer cell mediated cytotoxicity

• Purification:

  Affinity purification

• Dilution:

  IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:20000-1:40000

• Form:

  Liquid

• Buffer:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

• Modification:

  Unmodified

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype:

  IgG