MIC2 Rabbit Polyclonal Antibody

• Background :

  The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus. [provided by RefSeq, Mar 2016], function:Involved in T-cell adhesion processes. It is involved in spontaneous rosette formation with erythrocytes., miscellaneous:The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes., PTM:Extensively O-glycosylated., similarity:Belongs to the CD99 family.

• Product Name Alternative :

  CD99; MIC2; MIC2X; MIC2Y; CD99 antigen; 12E7; E2 antigen; Protein MIC2; T-cell surface glycoprotein E2; CD antigen CD99

• Gene Name :

  CD99

• Gene ID :

  4267

• Swiss Prot :

  P14209

• Host :

  Rabbit

• Reactivity :

  Human, Rat, Mouse

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  ICC/IF, ELISA

• Field of Research :

  Cell adhesion molecules (CAMs) ; Leukocyte transendothelial migration

• Purification :

  Affinity purification

• Dilution :

  ICC/IF 1:200-1:1000, ELISA 1:5000-1:10000

• Form :

  Liquid

• Buffer :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

• Modification :

  Unmodified

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype :

  IgG