T2R3 Rabbit Polyclonal Antibody

• Background:

  This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. These apparently intronless taste receptor genes encode a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008], function:Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5., miscellaneous:Several bitter taste receptors are expressed in a single taste receptor cell., similarity:Belongs to the G-protein coupled receptor T2R family., tissue specificity:Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. Expressed in the antrum and fundus (part of the stomach), duodenum and in gastric endocrine cells.

• Product Name Alternative:

  TAS2R3; Taste receptor type 2 member 3; T2R3

• Gene Name:

  TAS2R3

• Gene ID:

  50831

• Swiss Prot:

  Q9NYW6

• Host:

  Rabbit

• Reactivity:

  Human, Rat, Mouse

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  ICC/IF, ELISA

• Field of Research:

  Taste transduction

• Purification:

  Affinity purification

• Dilution:

  ICC/IF 1:200-1:1000, ELISA 1:10000-1:20000

• Form:

  Liquid

• Buffer:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

• Modification:

  Unmodified

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype:

  IgG