TLE2 Rabbit Polyclonal Antibody

• Background:

  Function:Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES., similarity:Belongs to the WD repeat Groucho/TLE family., similarity:Contains 6 WD repeats., subunit:Homooligomer and heterooligomer with other family members. Binds LEF1, TCF7, TCF7L1, TCF7L2, UTY, HES1 and HES5., tissue specificity:In all tissues examined, mostly in heart, brain, and muscle., function:Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES., similarity:Belongs to the WD repeat Groucho/TLE family., similarity:Contains 6 WD repeats., subunit:Homooligomer and heterooligomer with other family members. Binds LEF1, TCF7, TCF7L1, TCF7L2, UTY, HES1 and HES5., tissue specificity:In all tissues examined, mostly in heart, brain, and muscle.

• Product Name Alternative:

  TLE2; Transducin-like enhancer protein 2; Enhancer of split groucho-like protein 2; ESG2

• Gene Name:

  TLE2

• Gene ID:

  7089

• Swiss Prot:

  Q04725

• Host:

  Rabbit

• Reactivity:

  Human, Rat, Mouse

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, ICC/IF, ELISA

• Purification:

  Affinity purification

• Dilution:

  WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:10000-1:20000

• Form:

  Liquid

• Buffer:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

• Modification:

  Unmodified

• Molecular Weight:

  110kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype:

  IgG