RBAK Rabbit Polyclonal Antibody

• Background:

  This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus. [provided by RefSeq, Mar 2011], function:May repress E2F-dependent transcription. May promote AR-dependent transcription., similarity:Belongs to the krueppel C2H2-type zinc-finger protein family., similarity:Contains 1 KRAB domain., similarity:Contains 16 C2H2-type zinc fingers., subunit:Interacts with AR and RB1. May also interact with other nuclear hormone receptors such as NR3C1/GR., tissue specificity:Expressed in bone, brain, heart, kidney, liver, lung, pancreas and placenta.

• Product Name Alternative:

  RBAK; ZNF769; RB-associated KRAB zinc finger protein; RB-associated KRAB repressor; hRBaK; Zinc finger protein 769

• Gene Name:

  RBAK

• Gene ID:

  57786

• Swiss Prot:

  Q9NYW8

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, ICC/IF, ELISA

• Purification:

  Affinity purification

• Dilution:

  WB 1:500-1:2000, IHC 1:50-1:200, ICC/IF 1:50-1:200, ELISA 1:2000-1:20000

• Form:

  Liquid

• Buffer:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

• Modification:

  Unmodified

• Molecular Weight:

  85kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype:

  IgG