RIN3 Rabbit Polyclonal Antibody

• Background:

  Summary: This protein encoded by this gene is a member of the RIN family of Ras interaction-interference proteins, which are binding partners to the RAB5 small GTPases. The protein functions as a guanine nucleotide exchange for RAB5B and RAB31. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016], caution:The region from Asp-168 to Pro-327 is deduced from the genomic sequence by similarity to the mouse sequence., function:Potential Ras effector protein. May function as a guanine nucleotide exchange (GEF), by exchanging bound GDP for free GTP., similarity:Belongs to the RIN (Ras interaction/interference) family., similarity:Contains 1 Ras-associating domain., similarity:Contains 1 SH2 domain., similarity:Contains 1 VPS9 domain., subcellular location:Activation of tyrosine phosphorylation signaling induces translocation to cytoplasmic vesicles., subunit:Interacts with RAB5B and BIN1., tissue specificity:Widely expressed.

• Product Name Alternative:

  RIN3; Ras and Rab interactor 3; Ras interaction/interference protein 3

• Gene Name:

  RIN3

• Gene ID:

  79890

• Swiss Prot:

  Q8TB24

• Host:

  Rabbit

• Reactivity:

  Human, Rat, Mouse

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, ELISA

• Purification:

  Affinity purification

• Dilution:

  WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:2000-1:20000

• Form:

  Liquid

• Buffer:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

• Modification:

  Unmodified

• Molecular Weight:

  107kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype:

  IgG