CD64 Rabbit Polyclonal Antibody

• Background:

  This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq, Jul 2008], function:High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses., online information:FCGR1A mutation db, PTM:N-glycosylated., PTM:Phosphorylated on serine residues., similarity:Belongs to the immunoglobulin superfamily. FCGR1 family., similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains., subcellular location:Stabilized at the cell membrane through interaction with FCER1G., subunit:Interacts with FCERG1; forms a functional signaling complex. Interacts with FLNA; prevents FCGR1A degradation. Interacts with EPB41L2, LAT and PPL., tissue specificity:Monocyte/macrophage specific.

• Product Name Alternative:

  High affinity immunoglobulin gamma Fc receptor I (IgG Fc receptor I; Fc-gamma RI; FcRI; Fc-gamma RIA; FcgammaRIa; CD antigen CD64)

• Gene Name:

  FCGR1A FCG1 FCGR1 IGFR1

• Gene ID:

  2209

• Swiss Prot:

  P12314

• Host:

  Rabbit

• Reactivity:

  Human, Rat, Mouse

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, ICC/IF, ELISA

• Field of Research:

  Hematopoietic cell lineage; Fc gamma R-mediated phagocytosis; Systemic lupus erythematosus

• Purification:

  Affinity purification

• Dilution:

  WB 1:500-1:2000, IHC 1:50-1:200, ICC/IF 1:50-1:200, ELISA 1:10000-1:20000

• Form:

  Liquid

• Buffer:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

• Modification:

  Unmodified

• Molecular Weight:

  45kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype:

  IgG