CD64 Rabbit Polyclonal Antibody

CAT: 1444-APRab08431-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:1444-APRab08431-01Size:20 µL
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Background
This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq, Jul 2008], function:High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses., online information:FCGR1A mutation db, PTM:N-glycosylated., PTM:Phosphorylated on serine residues., similarity:Belongs to the immunoglobulin superfamily. FCGR1 family., similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains., subcellular location:Stabilized at the cell membrane through interaction with FCER1G., subunit:Interacts with FCERG1; forms a functional signaling complex. Interacts with FLNA; prevents FCGR1A degradation. Interacts with EPB41L2, LAT and PPL., tissue specificity:Monocyte/macrophage specific.
Product Name Alternative
High affinity immunoglobulin gamma Fc receptor I (IgG Fc receptor I; Fc-gamma RI; FcRI; Fc-gamma RIA; FcgammaRIa; CD antigen CD64)
Gene Name
FCGR1A FCG1 FCGR1 IGFR1
Gene ID
2209
Swiss Prot
P12314
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Field of Research
Hematopoietic cell lineage; Fc gamma R-mediated phagocytosis; Systemic lupus erythematosus
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, ICC/IF 1:50-1:200, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
45kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG

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