CD50 Rabbit Polyclonal Antibody

CAT: 1444-APRab08413-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:1444-APRab08413-01Size:20 µL
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Background
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016], function:ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2) . ICAM3 is also a ligand for integrin alpha-D/beta-2., online information:ICAM-3, PTM:N-glycosylated; glycans consist of a mixture of tri- and tetra-antennary complex-type chains and high-mannose chains., PTM:Upon stimulation by a physiologic stimuli becomes rapidly and transiently phosphorylated on serine residues., similarity:Belongs to the immunoglobulin superfamily. ICAM family., similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
Product Name Alternative
ICAM3; Intercellular adhesion molecule 3; ICAM-3; CDw50; ICAM-R; CD antigen CD50
Gene Name
ICAM3
Gene ID
3385
Swiss Prot
P32942
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ICC/IF, ELISA
Field of Research
Cell adhesion molecules (CAMs)
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ICC/IF 1:200-1:1000, ELISA 1:5000-1:10000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
42-60kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG

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