AIM2 Rabbit Polyclonal Antibody

• Background:

  AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2. [provided by RefSeq, Jul 2008], disease:Defects in AIM2 may be a cause of microsatellite unstable colon cancers., function:Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity., induction:By interferon gamma., similarity:Belongs to the HIN-200 family., similarity:Contains 1 DAPIN domain., similarity:Contains 1 HIN-200 domain., subunit:Homodimer., tissue specificity:Expressed in spleen, small intestine, peripheral blood leukocytes, and testis.

• Product Name Alternative:

  AIM2; Interferon-inducible protein AIM2; Absent in melanoma 2

• Gene Name:

  AIM2

• Gene ID:

  9447

• Swiss Prot:

  O14862

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, ICC/IF, ELISA

• Field of Research:

  Cytosolic DNA-sensing pathway

• Purification:

  Affinity purification

• Dilution:

  WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:200-1:1000, ELISA 1:20000-1:40000

• Form:

  Liquid

• Buffer:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

• Modification:

  Unmodified

• Molecular Weight:

  39kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype:

  IgG