CTGF Rabbit Polyclonal Antibody

• Background:

  The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009], function:Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis., similarity:Belongs to the CCN family., similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain., similarity:Contains 1 IGFBP N-terminal domain., similarity:Contains 1 TSP type-1 domain., similarity:Contains 1 VWFC domain., subunit:Monomer.

• Product Name Alternative:

  Connective tissue growth factor (CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP-8)

• Gene Name:

  CTGF CCN2 HCS24 IGFBP8

• Gene ID:

  1490

• Swiss Prot:

  P29279

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC, ICC/IF, ELISA

• Purification:

  Affinity purification

• Dilution:

  IHC 1:50-1:200, ICC/IF 1:50-1:200, ELISA 1:10000-1:20000

• Form:

  Liquid

• Buffer:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

• Modification:

  Unmodified

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype:

  IgG