APLF Rabbit Polyclonal Antibody

• Background :

  C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks (Iles et al., 2007 [PubMed 17353262]) .[supplied by OMIM, Mar 2008], domain:The FHA-like domain mediates interaction with XRCC1 and XRCC4., function:Involved in single-strand and double-strand DNA break repair., PTM:Phosphorylated in an ATM-dependent manner upon double-strand DNA break., similarity:Contains 1 FHA-like domain., similarity:Contains 2 C2H2-type zinc fingers., subcellular location:Colocalizes with XRCC1 at sites of DNA damage., subunit:Interacts with XRCC1. May also interact with XRCC4 and XRCC5.

• Product Name Alternative :

  APLF; C2orf13; PALF; XIP1; Aprataxin and PNK-like factor; Apurinic-apyrimidinic endonuclease APLF; PNK and APTX-like FHA domain-containing protein; XRCC1-interacting protein 1

• Gene Name :

  APLF

• Gene ID :

  200558

• Swiss Prot :

  Q8IW19

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB, IHC, ICC/IF, ELISA

• Purification :

  Affinity purification

• Dilution :

  WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:20000-1:40000

• Form :

  Liquid

• Buffer :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

• Modification :

  Unmodified

• Molecular Weight :

  57kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype :

  IgG