EEF2K Rabbit Polyclonal Antibody

• Background :

  This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq, Jul 2008], catalytic activity:ATP + [elongation factor 2] = ADP + [elongation factor 2] phosphate., enzyme regulation:Undergoes calcium/calmodulin-dependent intramolecular autophosphorylation, and this results in it becoming partially calcium/calmodulin-independent., function:Phosphorylates eukaryotic elongation factor-2. Binds calmodulin., similarity:Belongs to the protein kinase superfamily. Alpha-type protein kinase family., similarity:Contains 1 alpha-type protein kinase domain., subunit:Monomer or homodimer .

• Product Name Alternative :

  EEF2K; Eukaryotic elongation factor 2 kinase; eEF-2 kinase; eEF-2K; Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase

• Gene Name :

  EEF2K

• Gene ID :

  29904

• Swiss Prot :

  O00418

• Host :

  Rabbit

• Reactivity :

  Human, Rat

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB, IHC, ICC/IF, ELISA

• Field of Research :

  AMPK

• Purification :

  Affinity purification

• Dilution :

  WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:10000-1:20000

• Form :

  Liquid

• Buffer :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

• Modification :

  Unmodified

• Molecular Weight :

  105kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype :

  IgG