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Gads Rabbit Polyclonal Antibody

CAT: 1444-APRab11253-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:1444-APRab11253-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014], function:Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc., similarity:Belongs to the GRB2/sem-5/DRK family., similarity:Contains 1 SH2 domain., similarity:Contains 2 SH3 domains., subunit:Interacts with phosphorylated LIME1 upon TCR activation (By similarity) . Interacts with phosphorylated LAT and LAX1 upon TCR activation. Interacts with SHB.
Product Name Alternative
GRAP2; GADS; GRB2L; GRID; GRB2-related adapter protein 2; Adapter protein GRID; GRB-2-like protein; GRB2L; GRBLG; GRBX; Grf40 adapter protein; Grf-40; Growth factor receptor-binding protein; Hematopoietic cell-associated adapter protein Grp
Gene Name
GRAP2
Gene ID
9402
Swiss Prot
O75791
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Field of Research
T_Cell_Receptor
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:20000-1:40000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
38kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG

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