CD66e Rabbit Polyclonal Antibody

• Background :

  This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015], function:Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins., PTM:Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate., similarity:Belongs to the immunoglobulin superfamily. CEA family., similarity:Contains 7 Ig-like (immunoglobulin-like) domains., subunit:Homodimer. Binding of E.coli Dr adhesins leads to dissociation of the homodimer., tissue specificity:Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.

• Product Name Alternative :

  CEACAM5; CEA; Carcinoembryonic antigen-related cell adhesion molecule 5; Carcinoembryonic antigen; CEA; Meconium antigen 100; CD66e

• Gene Name :

  CEACAM5

• Gene ID :

  1048

• Swiss Prot :

  P06731

• Host :

  Rabbit

• Reactivity :

  Human, Rat, Mouse

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB, IHC, ICC/IF, ELISA

• Purification :

  Affinity purification

• Dilution :

  WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:10000-1:20000

• Form :

  Liquid

• Buffer :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

• Modification :

  Unmodified

• Molecular Weight :

  76kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype :

  IgG