Calmodulin Rabbit Polyclonal Antibody

CAT: 1444-APRab07860-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:1444-APRab07860-01Size:20 µL
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Background
This gene encodes a member of the EF-hand calcium-binding protein family. It is one of three genes which encode an identical calcium binding protein which is one of the four subunits of phosphorylase kinase. Two pseudogenes have been identified on chromosome 7 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009], function:Calmodulin mediates the control of a large number of enzymes and other proteins by Ca (2+) . Among the enzymes to be stimulated by the calmodulin-Ca (2+) complex are a number of protein kinases and phosphatases. Together with CEP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis., miscellaneous:This protein has four functional calcium-binding sites., PTM:Phosphorylation results in a decreased activity., PTM:Ubiquitination results in a strongly decreased activity., similarity:Belongs to the calmodulin family., similarity:Contains 4 EF-hand domains., subcellular location:Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules., subunit:Interacts with MYO1C (By similarity) . Interacts with CEP97, CEP110, TTN/titin and SRY.
Product Name Alternative
CALM1; CALM; CAM; CAM1; CALM2; CAM2; CAMB; CALM3; CALML2; CAM3; CAMC; CAMIII; Calmodulin; CaM
Gene Name
CALM1
Gene ID
801/805/808
Swiss Prot
P62158
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Field of Research
Calcium; Phosphatidylinositol signaling system; Oocyte meiosis; Vascular smooth muscle contraction; Long-term potentiation; Neurotrophin; Olfactory transduction; Insulin_Receptor; GnRH; Melanogenesis; Alzheimer's disease; Glioma
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG

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