M-CSF Receptor Rabbit Monoclonal Antibody

• Background:

  Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development.

• Product Name Alternative:

  M-CSF Receptor; CSF-1-R; CSF-1R; M-CSF-R; Proto-oncogene c-Fms; CD115

• Gene Name:

  M-CSF Receptor

• Gene ID:

  12978

• Swiss Prot:

  P09581

• Host:

  Rabbit

• Reactivity:

  Human

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Applications:

  WB

• Purification:

  Affinity Purification

• Dilution:

  WB 1:500-1:1000

• Form:

  Liquid

• Buffer:

  Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 109 kDa; Observed MW: 109 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

• Isotype:

  IgG