ENSA Rabbit Monoclonal Antibody

• Background:

  Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase . Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K (ATP) channel currents.

• Product Name Alternative:

  ARPP-19e

• Gene Name:

  ENSA

• Gene ID:

  2029

• Swiss Prot:

  O43768

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Applications:

  WB

• Purification:

  Affinity Purification

• Dilution:

  WB 1:500-1:1000

• Form:

  Liquid

• Buffer:

  Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 13 kDa; Observed MW: 13 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

• Isotype:

  IgG