IL-33 Rabbit Monoclonal Antibody

• Background:

  Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury.

• Product Name Alternative:

  Il-33; Il1f11; NF-HEV; 9230117N10Rik

• Gene Name:

  IL-33

• Gene ID:

  77125

• Swiss Prot:

  Q8BVZ5

• Host:

  Rabbit

• Reactivity:

  Mouse, Rat

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, ICC/IF, FC

• Purification:

  Affinity Purification

• Dilution:

  WB 1:500-1:2000, IHC 1:200-1:2000, ICC/IF 1:200-1:500, FC 1:200-1:500

• Form:

  Liquid

• Buffer:

  Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW:30 kDa; Observed MW:30 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

• Isotype:

  IgG