Cripto1 Rabbit Monoclonal Antibody

• Background :

  GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated TDGF1 acts as a Nodal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells (PubMed:27881714) . Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm (PubMed:11909953) .2 Publications GO - Molecular functioni

• Product Name Alternative :

  V1S4; TCRGV4

• Gene Name :

  Cripto1

• Gene ID :

  6977

• Swiss Prot :

  P13385

• Host :

  Rabbit

• Reactivity :

  Human

• Clonality :

  Monoclonal

• Conjugation :

  Unconjugated

• Applications :

  WB, IP

• Purification :

  Affinity Purification

• Dilution :

  WB 1:500-1:2000, IP 1:20-1:50

• Form :

  Liquid

• Buffer :

  Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Modification :

  Unmodified

• Molecular Weight :

  Calculated MW:21 kDa; Observed MW:18, 20 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

• Isotype :

  IgG