CDCA5 Rabbit Monoclonal Antibody

• Background:

  Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of WAPL which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Required for efficient DNA double-stranded break repair.

• Product Name Alternative:

  SORORIN

• Gene Name:

  CDCA5

• Gene ID:

  113130

• Swiss Prot:

  Q96FF9

• Host:

  Rabbit

• Reactivity:

  Human

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, ICC/IF, FC

• Purification:

  Affinity Purification

• Dilution:

  WB 1:1000-1:5000, IHC 1:50-1:100, ICC/IF 1:100-1:200, FC 1:50-1:200

• Form:

  Liquid

• Buffer:

  Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW:28 kDa; Observed MW:35 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

• Isotype:

  IgG