PDE1B Rabbit Monoclonal Antibody

• Background:

  The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

• Product Name Alternative:

  PDE1B1; PDES1B; HEL-S-79p

• Gene Name:

  PDE1B

• Gene ID:

  5153

• Swiss Prot:

  Q01064

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Signal Transduction

• Purification:

  Affinity Purification

• Dilution:

  WB 1:500-1:1000

• Form:

  Liquid

• Buffer:

  50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 61 kDa; Observed MW: 61 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype:

  IgG