ERK2 Rabbit Monoclonal Antibody

• Background:

  Act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of ERK2 requires its phosphorylation by upstream kinases. ERK2 is located in the cytoplasm of resting cells and translocates into the nucleus upon extracellular stimuli by active transport of a dimer. ERK2 is essential for placental development and ERK2 in the trophoblast compartment may be indispensable for the vascularization of the labyrinth.

• Product Name Alternative:

  ERK; p38; p40; p41; ERT1; MAPK2; PRKM1; P42MAPK; p41mapk; MAPK

• Gene Name:

  MAPK1

• Gene ID:

  5594

• Swiss Prot:

  P28482

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, ICC/IF, IP

• Field of Research:

  Neuroscience

• Purification:

  Affinity Purification

• Dilution:

  WB 1:500-1:1000, IHC 1:50-1:100, ICC/IF 1:50-1:200, IP 1:20-1:50

• Form:

  Liquid

• Buffer:

  50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 41 kDa; Observed MW: 41 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype:

  IgG