Recombinant Human BMP-4

• Background :

  Bone morphogenic protein-4 (BMP-4) is one of nine structurally related BMPs belonging to the transforming growth factor-beta (TGF-beta) superfamily of secreted proteins. Mature BMP-4 is a dimer that binds to a multimeric transmembrane receptor with serine/threonine kinase activity. BMP-4 has important roles as a signalling molecule in embryonic tissues, including the developing central and peripheral nervous system, musculature and skeleton. BMP-4 as well as its receptors and their signal transduction pathways play a crucial role in the control of the differentiation and proliferation of the different cell types that constitute the anterior pituitary.

• Product Name Alternative :

  Bone morphogenetic protein 4; BMP-4; BMP4; BMP2B; DVR4

• Accession Number :

  P12644

• Host :

  E.coli

• Endotoxin :

  <0.01 EU/µg as determined by LAL test.

• Purity :

  Greater than 95% as determined by reducing SDS-PAGE

• Form :

  Liquid

• Reconstitution :

  0

• Molecular Weight :

  13.3 KDa

• Shipping Conditions :

  The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

• Storage Conditions :

  Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

• Formulation :

  Supplied as a 0.2 μm filtered solution of 4mM HCl.

• Construct :

  Recombinant Human Bone morphogenetic protein 4 is produced by our E.coli expression system and the target gene encoding Ser293-Arg408.

• Species :

  Human