RegisterLogin

Recombinant Human TSLP

CAT: 1444-PEH1738-01Size: 10 µgDry Ice: NoHazardous: No
CAT#:1444-PEH1738-01Size:10 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino acids (aa) signal sequence and 131 aa mature region. Human TSLP has two isoforms lfTSLP and sfTSLP produced by alternative splicing . lfTSLP is expressed in a number of tissues including heart, liver and prostate, and sfTSLP (63aa) is predominantly expressed in keratinocytes of oral mucosa, skin and in salivary glands. In aa sequence level, Human TSLP displays about 43% identity with mouse TSLP.TSLP is a cytokine that functions mainly on myeloid cells; it induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c (+) dendritic cells.TSLP has proliferative effects on the myeloid cell line and may initiate asthma or atopic dermatitis responses by directly activating mast cells . TSLP signals cells via the interleukin-7 receptor-α chain (IL-7Rα), shared with IL-7, together with the TSLP receptor (TSLPR) subunit. Recent studies indicate that TSLP and its receptor are novel therapeutic targets for rheumatoid arthritis, for increased intraarticular TSLP concentrations in patients has caused chemotaxis and activation of arthritogenic T cells.
Product Name Alternative
Thymic stromal lymphopoietin; TSLP
Accession Number
Q969D9
Host
E.coli
Endotoxin
<1 EU/µg as determined by LAL test.
Purity
Greater than 95% as determined by reducing SDS-PAGE
Form
Lyophilized
Reconstitution
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Molecular Weight
15.1 KDa
Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Storage Conditions
Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Construct
Recombinant Human Thymic Stromal Lymphopoietin is produced by our E.coli expression system and the target gene encoding Tyr29-Gln159 is expressed.
Species
Human

Related Products

CatalogName
EMk27537Monkey TSLP (TSLP) ELISA Kit
PEV2124-01Recombinant Cynomolgus TSLP (C-6His)
PHM1640-01Recombinant Mouse TSLP (C-Fc)
PHM1739-01Recombinant Mouse TSLP R (C-6His)
PHM1740-01Recombinant Mouse TSLP R (C-Fc)
AMM83374-01TSLP Mouse Monoclonal Antibody
EH24529Human TSLP (Thymic Stromal Lymphopoietin) ELISA Kit
ER21501Rat TSLP (Thymic Stromal Lymphopoietin) ELISA Kit
EM22921Mouse TSLP (Thymic Stromal Lymphopoietin) ELISA Kit
PHH2398-01Recombinant Human TSLPR&IL-7RA Heterodimer (C-6His)

Alternative Products

CatalogName
E4A10C36Recombinant human TSLP
4896-20TSLP, human recombinant
TP727319TSLP Human Recombinant Protein
NBP2-35083-1mgRecombinant Human TSLP Protein
Pr23158-01Recombinant Human TSLP R
PROTQ969D9-100ugHuman TSLP Recombinant Protein
OPCA05406-20UGTSLP Recombinant Protein (Human)
MBS201144-01Recombinant TSLP

Popular Products