Products for Research Use Only
RegisterLogin

Recombinant Mouse CD31 (C-6His)

CAT: 1444-PHM1336-01Size: 10 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1444-PHM1336-01Size:10 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Platelet endothelial cell adhesion molecule (PECAM-1, CD31) is a type I transmembrane glycoprotein adhesion molecule in the immunoglobulin superfamily. PECAM-1 is concentrated at cell junctions and is required for transendothelial migration (TEM) . The extracellular domain (ECD) of PECAM-1 has ten potential N-linked glycosylation sites and six C2-type Ig-like domains, the first of which is critical for adhesion and extravasation. The cytoplasmic domain contains immunoregulatory tyrosine-based inhibitory and switch motifs (ITIM, ITSM) that mediate both inhibition and activation via phosphotyrosine-mediated engagement of SH2-containing signaling molecules. Expression is restricted to cells involved in circulation, especially endothelial cells, platelets, monocytes, neutrophils and lymphocyte subsets. PECAM-1 participates with other adhesion molecules in some functions, but is the critical molecule for TEM. Homotypic PECAM-1 adhesion in trans, combined with cycling of PECAM-1 to and from surface-connected endothelial cell vesicles, leads leukocytes across endothelial tight junctions.
Product Name Alternative
Platelet endothelial cell adhesion molecule; PECAM-1; CD31; Pecam1; Pecam
Accession Number
Q08481
Host
Human Cells
Endotoxin
<1 EU/µg as determined by LAL test.
Purity
Greater than 95% as determined by reducing SDS-PAGE
Form
Lyophilized
Reconstitution
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Molecular Weight
63.4 KDa
Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Storage Conditions
Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, 5mM EDTA, pH7.4.
Construct
Recombinant Mouse Platelet Endothelial Cell Adhesion Molecule is produced by our Mammalian expression system and the target gene encoding Glu18-Lys590 is expressed with a 6His tag at the C-terminus.
Species
Mouse

Related Products

CatalogName
PHM1695-01Recombinant Mouse CD30 (C-6His)
PHM1867-01Recombinant Mouse CD38 (C-6His)
PHM0574-01Recombinant Mouse CD39 (C-6His)
PHH2158-01Recombinant Human CD3D&CD3E Heterodimer (C-6His)
PHH2001-01Recombinant Human CD30 (C-6His)
PHH1866-01Recombinant Human CD38 (C-6His)
PHH0328-01Recombinant Human CD316 (C-6His)
PHH1987-01Recombinant Human CD3D (C-6His)
PHH0344-01Recombinant Human CD3E (C-6His)
PHV0343-01Recombinant Cynomolgus CD3d (C-6His)

Alternative Products

CatalogName
CU23-01Recombinant Mouse CD31 (C-6His)
CU23-50ugRecombinant Mouse Platelet Endothelial Cell Adhesion Molecule/CD31/PECAM-1 (C-6His)
MBS7621668-01Recombinant Mouse CD31
32-9582-500Recombinant Mouse Hemopexin (C-6His)
32-7872-10Recombinant Mouse LAIR1 (C-6His)
32-7829-10Recombinant Mouse ST6GALNAC2 (C-6His)
32-11283-10Recombinant Mouse Mesothelin (C-6His)
32-11265-50Recombinant Mouse HGF (C-6His)
32-11256-50Recombinant Mouse Tpsb2 (C-6His)
32-11171-10Recombinant Mouse BTNL4 (C-6His)

Popular Products