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Recombinant Human CTH

CAT: 1444-PEH0489-01Size: 10 µgDry Ice: YesHazardous: No
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CAT#:1444-PEH0489-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cystathionine Gamma-Lyase (CTH) belongs to the trans-sulfuration enzymes family. CTH exists as a homotetramer and interacts with CALM in a calcium-dependent manner. CTH breaks down cystathionine into cysteine, ammonia and 2-oxobutanoate. CTH catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine and has broad substrate specificity. Defects in CTH will lead to cystathioninuria, which is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine.
Product Name Alternative
Cystathionine Gamma-Lyase; Cysteine-Protein Sulfhydrase; Gamma-Cystathionase; CTH
Accession Number
P32929
Host
E.coli
Endotoxin
<1 EU/µg as determined by LAL test.
Purity
Greater than 95% as determined by reducing SDS-PAGE
Form
Liquid
Molecular Weight
44.7 KDa
Shipping Conditions
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Storage Conditions
Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 8% Sucrose, 0.05% Tween 80, pH8.0.
Construct
Recombinant Human Cystathionine Gamma-Lyase is produced by our E.coli expression system and the target gene encoding Met1-Ser405 is expressed.
Species
Human

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