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Nepodin

CAT: 0804-HY-N5018-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N5018-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nepodin (Musizin) is a quinone oxidoreductase (PfNDH2) inhibitor isolate from Rumex crispus[1].Nepodin (Musizin) stimulates the translocation of GLUT4 to the plasma membrane by activation of AMPK[2].Nepodin (Musizin) has antidiabetic and antimalarial activities.
CAS Number
3785-24-8
Product Name Alternative
Musizin
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
AMPK; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Epigenetics; PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nepodin.html
Purity
99.71
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CC(C1=C(C)C=C2C=CC=C(O)C2=C1O)=O
Molecular Formula
C13H12O3
Molecular Weight
216.23
Precautions
H302, H315, H319, H335
References & Citations
[1]Lee KH, et al. Antimalarial activity of nepodin isolated from Rumex crispus. Arch Pharm Res. 2013 Apr;36 (4) :430-5.|[2]Ha BG, et al. Antidiabetic effect of nepodin, a component of Rumex roots, and its modes of action in vitro and in vivo. Biofactors. 2014 Jul-Aug;40 (4) :436-47.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Plasmodium

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