Hexestrol

• Description:

  Hexestrol is a nonsteroidal synthetic estrogen, with a Ki of 0.06 and 0.06 nM for estrogen receptor alpha (ERα) and ERβ. Hexestrol can be used for the research of the diseases caused by estrogen deficiencym, and it also can increase the weight of cattle[1][2][3].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Estrogen Receptor/ERR

• Type:

  Reference compound

• Related Pathways:

  Vitamin D Related/Nuclear Receptor

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/hexestrol.html

• Concentration:

  10mM

• Purity:

  99.88

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CC[C@H](C1=CC=C(O)C=C1)[C@H](C2=CC=C(O)C=C2)CC

• Molecular Formula:

  C18H22O2

• Molecular Weight:

  270.37

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]HARDING FE, et, al. The oral use of hexestrol for estrogen deficiency. Am J Obstet Gynecol. 1946 May; 51: 660-5.|[2]Oliveira JM, et, al. Effects of hexestrol on mouse ovarian morphology and ovulation. Maturitas. 2008 Jun 20; 60 (2) : 153-7.|[3]Kuiper GG, et, al. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology. 1997 Mar;138 (3) :863-70.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  ERα; ERβ

• CAS Number:

  [84-16-2]