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TET-13

CAT: 0804-HY-169432Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-169432Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TET-13 is a positive allosteric modulator of GABAA receptor with an EC50 of 5.65 μM, lower than that of Etomidate (EC50: 9.29 μM) . TET-13 shows potent anesthetic effects in both mice and rats (ED50: 0.48 mg/kg and 0.69 mg/kg, respectively) [1].
UNSPSC
12352005
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tet-13.html
Smiles
COC(CSC(C1=CN=CN1[C@H](C)C2=CC=CC=C2)=O)=O
Molecular Formula
C15H16N2O3S
Molecular Weight
304.36
References & Citations
[1]Zhu, et al. Discovery of thioetomidate derivatives as rapid recovery hypnotics without adrenocortical suppression. Bioorganic chemistry. 2024, 154, 107997.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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