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CpxA | Conjugative plasmid expression Antibody

CAT: 0013-GTR17855764Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0013-GTR17855764Size:50 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal antibody to CpxA
Reactivity
Bacteria
Immunogen
Recombinant CpxA (residues 26 to 168) over-expressed as a N-terminal fusion with His (x6) -tag, which was removed prior to immunization. The antigen originates from enteropathogenic Yersinia pseudotuberculosis YPIII; B1JQV1, NCBI annotated locus tag YPK_4133.
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Molecular Biology
Purification
Serum
Dilution
WB: 1:2000
Form
Lyophilized
Molecular Weight
Expected: 51.8 , Apparent: 52-53 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
CpxA (Conjugative Plasmid Expression) is the 458 amino acid protein, a bacterial inner membrane histidine protein kinase, responsible for sensing misfolded proteins in the periplasm. It is part of CpxA/CpxR two component signal transduction system, where CpxR is the cognate response regulator. In sensing bacterial envelope stress, the Cpx pathway regulates the production of a number of periplasmic folding and trafficking factors to maintain outer membrane integrity. It is also responsible for global control of virulence factor expression. Alternative name: Integral membrane sensor signal transduction histidine kinase.
Tested Applications
WB
Host or Source
Rabbit

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