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CDC42 antibody

CAT: 0710-FNab11077Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab11077Size:100 µg
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Background
The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20.
Synonyms
Cell division control protein 42 homolog|G25K GTP-binding protein|CDC42
Gene ID
998
UniProt
P60953
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
Cell division cycle 42 (GTP binding protein, 25kDa)
Target
CDC42
Clonality
Monoclonal
Isotype
IgM
Field of Research
Immunology, Signal Transduction, Cell Division and Proliferation
Purification
Protein A affinity purified
Dilution
WB: 1:1000 - 1:5000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
21 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
2H2
Tested Applications
ELISA, WB

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