Biotin Anti-Mouse CD3 Antibody (17A2)

• Background:

  CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

• Synonyms:

  CD3| CD3E/D/G/Z| CD3e/d/g/z| T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain

• Gene ID:

  12502

• UniProt:

  P04235, P11942, P22646, P24161

• Host:

  Rat

• Reactivity:

  Mouse

• Target:

  Mouse CD3

• Clonality:

  Monoclonal

• Isotype:

  IgG2b κ

• Conjugation:

  Biotin

• Dilution:

  Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg/10⁶ cells in 100 μL volume].

• Form:

  Liquid

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Clone ID:

  17A2

• Tested Applications:

  FC