MTOR antibody

• Background:

  The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.

• Synonyms:

  Serine/threonine-protein kinase mTOR|FK506-binding protein 12-rapamycin complex-associated protein 1|FKBP12-rapamycin complex-associated protein|Mammalian target of rapamycin (mTOR) |Mechanistic target of rapamycin|Rapamycin and FKBP12 target 1|Rapamycin target protein 1|MTOR|FRAP|FRAP1|FRAP2|RAFT1|RAPT1

• Gene ID:

  2475

• UniProt:

  P42345

• Host:

  Mouse

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  FK506 binding protein 12-rapamycin associated protein 1

• Target:

  MTOR

• Clonality:

  Monoclonal

• Isotype:

  IgG2a

• Field of Research:

  Signal Transduction, Metabolism, Cardiovascular, Immunology, Developmental biology, Cell Division and Proliferation

• Purification:

  Protein A affinity purified

• Dilution:

  WB: 1:1000 - 1:10000; IHC: 1:500 - 1:2000; IF:1:200-1:800

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  290 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Clone ID:

  5G5

• Tested Applications:

  ELISA, WB, IHC, IF

• Immunogen Sequence:

  27-291aa