CD133 antibody

• Background:

  This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.

• Synonyms:

  Prominin-1|Antigen AC133|Prominin-like protein 1|PROM1|PROML1|CD133

• Gene ID:

  8842

• UniProt:

  O43490

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Prominin 1

• Target:

  CD133

• Clonality:

  Monoclonal

• Isotype:

  IgG1

• Purification:

  Protein A+G purification

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  115 kDa-120 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Clone ID:

  2H6

• Tested Applications:

  ELISA, WB, IHC