CD81 antibody

• Background:

  The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene.

• Synonyms:

  CD81 antigen|26 kDa cell surface protein TAPA-1|Target of the antiproliferative antibody 1|Tetraspanin-28 (Tspan-28) |CD81|TAPA1|TSPAN28

• Gene ID:

  975

• UniProt:

  P60033

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  CD81 molecule

• Target:

  CD81

• Clonality:

  Monoclonal

• Isotype:

  IgG1

• Field of Research:

  Immunology, Cardiovascular, Signal Transduction

• Purification:

  Protein A+G purified

• Dilution:

  WB: 1:500 - 1:2000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  22 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Clone ID:

  1H7

• Tested Applications:

  ELISA, WB