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METTL3 Antibody

CAT: 0667-KC-47503-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0667-KC-47503-01Size:50 μL
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Product Name Alternative
N6-adenosine-methyltransferase catalytic subunit, Methyltransferase-like protein 3, hMETTL3, N6-adenosine-methyltransferase 70 kDa subunit, MT-A70
Gene Name
METTL3
Gene ID
56339
UniProt
Q86U44
Antigen Species
Human
Reactivity
Human
Cross Reactivity
Not tested
Immunogen
Recombinant human METTL3
Target
PP-6131
Partner Proteins
N6-adenosine-methyltransferase catalytic subunit; Methyltransferase-like protein 3; hMETTL3; N6-adenosine-methyltransferase 70 kDa subunit; MT-A70
Clone
KCA035_10B1
Conjugation
Unconjugated
Applications
Top_WB
Validation
Top_WB
Homology
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Pig - 99%, Cynomolgus monkey - 100%
Purity
≥85%
Cores
HPTLVTYADHSKLSAMMGAVAEKKGPGEVAGTVTGQKRRAEQDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLLNQQSTKEQQSKKVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRKLHFRRIINKHTDESLGDCSFLNTCFHMDTCKYVHYEIDACMDSEAPGSKDHTPSQELALTQSVGGDSSADRLFPPQWICCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRRLNIPVLQDDGFLFLWVTGRAMELGRECLNLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGVKGNPQGFNQGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNVQPNWITLGNQ
Storage Temperature
Avoid repeated freeze-thaw cycles. Upon receipt, * 1 month when stored at 2 to 8 °C * 12 months when aliquoted and stored at -20 °C or lower
Identity Mouse
97%
Recombinant Antibody
Not recombinant
WB Dilution
1:1000
Formulation
Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Antibody Type
Monoclonal
Gene Name Synonym
MTA70
Target Alternative Name
METTL3
Panel Description
Ferroptosis
Host or Source
Mouse
Protein Name
Methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit
WB Description
Succeed
Shipping Temperature
Shipped at ambient temperature or with ice packs.
Isotype
IgG2a

UniProtKB · Q86U44

N(6)-adenosine-methyltransferase catalytic subunit METTL3

MTA70_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q86U44
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
METTL3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.1.1.348
Processing
—
Secondary accessions
O14736, Q86V05, Q9HB32
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Biological process

Biological rhythmsDifferentiationDNA damageImmunityInnate immunityOogenesisSpermatogenesis

Cellular component

CytoplasmNucleus

Molecular function

MethyltransferaseRNA-bindingTransferase

Ligand

S-adenosyl-L-methionine